{"id":1858,"date":"2026-02-07T19:48:10","date_gmt":"2026-02-07T10:48:10","guid":{"rendered":"https:\/\/dev.rftcjapan.org\/?page_id=1858"},"modified":"2026-02-27T13:22:38","modified_gmt":"2026-02-27T04:22:38","slug":"signs-and-symptoms","status":"publish","type":"page","link":"https:\/\/rftcjapan.org\/en\/about-breast-cancer\/signs-and-symptoms\/","title":{"rendered":"Signs and Symptoms"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"1858\" class=\"elementor elementor-1858\" data-elementor-post-type=\"page\">\n\t\t\t\t<div class=\"elementor-element elementor-element-43fbc20 e-flex e-con-boxed e-con e-parent\" data-id=\"43fbc20\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-3b1a002 elementor-align-justify elementor-mobile-align-justify elementor-hidden-desktop elementor-hidden-tablet elementor-widget elementor-widget-button\" data-id=\"3b1a002\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;sticky&quot;:&quot;top&quot;,&quot;sticky_offset_mobile&quot;:63,&quot;sticky_on&quot;:[&quot;mobile&quot;],&quot;sticky_offset&quot;:0,&quot;sticky_effects_offset&quot;:0,&quot;sticky_anchor_link_offset&quot;:0}\" data-widget_type=\"button.default\">\n\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"#elementor-action%3Aaction%3Doff_canvas%3Aopen%26settings%3DeyJpZCI6ImE3MzNhN2YiLCJkaXNwbGF5TW9kZSI6Im9wZW4ifQ%3D%3D\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-icon\">\n\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-ellipsis-h\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M328 256c0 39.8-32.2 72-72 72s-72-32.2-72-72 32.2-72 72-72 72 32.2 72 72zm104-72c-39.8 0-72 32.2-72 72s32.2 72 72 72 72-32.2 72-72-32.2-72-72-72zm-352 0c-39.8 0-72 32.2-72 72s32.2 72 72 72 72-32.2 72-72-32.2-72-72-72z\"><\/path><\/svg>\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">About Breast Cancer<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-a733a7f elementor-widget elementor-widget-off-canvas\" data-id=\"a733a7f\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;entrance_animation_mobile&quot;:&quot;none&quot;,&quot;exit_animation_mobile&quot;:&quot;none&quot;}\" data-widget_type=\"off-canvas.default\">\n\t\t\t\t\t\t\t<div id=\"off-canvas-a733a7f\" class=\"e-off-canvas\" role=\"dialog\" aria-hidden=\"true\" aria-label=\"Off-Canvas\" aria-modal=\"true\" inert=\"\" data-delay-child-handlers=\"true\">\n\t\t\t<div class=\"e-off-canvas__overlay\"><\/div>\n\t\t\t<div class=\"e-off-canvas__main\">\n\t\t\t\t<div class=\"e-off-canvas__content\">\n\t\t\t\t\t<div class=\"elementor-element elementor-element-64c3386 e-con-full e-flex e-con e-child\" data-id=\"64c3386\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-1d4dc4b elementor-view-stacked elementor-shape-circle elementor-widget elementor-widget-icon\" data-id=\"1d4dc4b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"icon.default\">\n\t\t\t\t\t\t\t<div class=\"elementor-icon-wrapper\">\n\t\t\t<a class=\"elementor-icon\" href=\"#elementor-action%3Aaction%3Doff_canvas%3Aclose%26settings%3DeyJpZCI6ImE3MzNhN2YiLCJkaXNwbGF5TW9kZSI6ImNsb3NlIn0%3D\">\n\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-plus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H272V64c0-17.67-14.33-32-32-32h-32c-17.67 0-32 14.33-32 32v144H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h144v144c0 17.67 14.33 32 32 32h32c17.67 0 32-14.33 32-32V304h144c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg>\t\t\t<\/a>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f052226 elementor-widget elementor-widget-template\" data-id=\"f052226\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"template.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-template\">\n\t\t\t\t\t<div data-elementor-type=\"section\" data-elementor-id=\"3044\" class=\"elementor elementor-3044\" data-elementor-post-type=\"elementor_library\">\n\t\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-2330\" class=\"elementor-element elementor-element-fd830c6 e-con-full e-grid e-con e-child\" data-id=\"fd830c6\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-2330\" class=\"elementor-element elementor-element-3717cd6 e-con-full e-flex e-con e-child\" data-id=\"3717cd6\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-e6c4d06 elementor-widget elementor-widget-heading\" data-id=\"e6c4d06\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">Breast Cancer Basics<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c84b33f elementor-nav-menu--dropdown-none elementor-widget elementor-widget-nav-menu\" data-id=\"c84b33f\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;layout&quot;:&quot;vertical&quot;,&quot;submenu_icon&quot;:{&quot;value&quot;:&quot;&lt;i aria-hidden=\\&quot;true\\&quot; class=\\&quot;\\&quot;&gt;&lt;\\\/i&gt;&quot;,&quot;library&quot;:&quot;&quot;}}\" data-widget_type=\"nav-menu.default\">\n\t\t\t\t\t\t\t\t<nav aria-label=\"\u30e1\u30cb\u30e5\u30fc\" class=\"elementor-nav-menu--main elementor-nav-menu__container elementor-nav-menu--layout-vertical e--pointer-none\">\n\t\t\t\t<ul id=\"menu-1-c84b33f\" class=\"elementor-nav-menu sm-vertical\"><li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2517\"><a href=\"https:\/\/rftcjapan.org\/en\/about-breast-cancer\/what-is-breast-cancer\/\" class=\"elementor-item\">What is Breast Cancer?<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2515\"><a href=\"https:\/\/rftcjapan.org\/en\/about-breast-cancer\/breast-cancer-statistics-global-japan\/\" class=\"elementor-item\">Breast Cancer Statistics (Global &amp; Japan)<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2516\"><a href=\"https:\/\/rftcjapan.org\/en\/about-breast-cancer\/understanding-the-risk-of-breast-cancer\/\" class=\"elementor-item\">Understanding the Risk of Breast Cancer<\/a><\/li>\n<\/ul>\t\t\t<\/nav>\n\t\t\t\t\t\t<nav class=\"elementor-nav-menu--dropdown elementor-nav-menu__container\" aria-hidden=\"true\">\n\t\t\t\t<ul id=\"menu-2-c84b33f\" class=\"elementor-nav-menu sm-vertical\"><li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2517\"><a href=\"https:\/\/rftcjapan.org\/en\/about-breast-cancer\/what-is-breast-cancer\/\" class=\"elementor-item\" tabindex=\"-1\">What is Breast Cancer?<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2515\"><a href=\"https:\/\/rftcjapan.org\/en\/about-breast-cancer\/breast-cancer-statistics-global-japan\/\" class=\"elementor-item\" tabindex=\"-1\">Breast Cancer Statistics (Global &amp; Japan)<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2516\"><a href=\"https:\/\/rftcjapan.org\/en\/about-breast-cancer\/understanding-the-risk-of-breast-cancer\/\" class=\"elementor-item\" tabindex=\"-1\">Understanding the Risk of Breast Cancer<\/a><\/li>\n<\/ul>\t\t\t<\/nav>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-2330\" class=\"elementor-element elementor-element-67a9bd1 e-con-full e-flex e-con e-child\" data-id=\"67a9bd1\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-ed0de9e elementor-widget elementor-widget-heading\" data-id=\"ed0de9e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">Diagnosis &amp; Staging<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c981917 elementor-nav-menu--dropdown-none elementor-widget elementor-widget-nav-menu\" data-id=\"c981917\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;layout&quot;:&quot;vertical&quot;,&quot;submenu_icon&quot;:{&quot;value&quot;:&quot;&lt;svg aria-hidden=\\&quot;true\\&quot; class=\\&quot;e-font-icon-svg e-fas-caret-down\\&quot; viewBox=\\&quot;0 0 320 512\\&quot; xmlns=\\&quot;http:\\\/\\\/www.w3.org\\\/2000\\\/svg\\&quot;&gt;&lt;path d=\\&quot;M31.3 192h257.3c17.8 0 26.7 21.5 14.1 34.1L174.1 354.8c-7.8 7.8-20.5 7.8-28.3 0L17.2 226.1C4.6 213.5 13.5 192 31.3 192z\\&quot;&gt;&lt;\\\/path&gt;&lt;\\\/svg&gt;&quot;,&quot;library&quot;:&quot;fa-solid&quot;}}\" data-widget_type=\"nav-menu.default\">\n\t\t\t\t\t\t\t\t<nav aria-label=\"\u30e1\u30cb\u30e5\u30fc\" class=\"elementor-nav-menu--main elementor-nav-menu__container elementor-nav-menu--layout-vertical e--pointer-none\">\n\t\t\t\t<ul id=\"menu-1-c981917\" class=\"elementor-nav-menu sm-vertical\"><li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2521\"><a href=\"https:\/\/rftcjapan.org\/en\/about-breast-cancer\/signs-and-symptoms\/\" class=\"elementor-item\">Signs and Symptoms<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2522\"><a href=\"https:\/\/rftcjapan.org\/en\/about-breast-cancer\/the-stages-of-breast-cancer\/\" class=\"elementor-item\">The Stages of Breast Cancer<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2523\"><a href=\"https:\/\/rftcjapan.org\/en\/about-breast-cancer\/tumor-size-and-staging\/\" class=\"elementor-item\">Tumor Size and Staging<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2520\"><a href=\"https:\/\/rftcjapan.org\/en\/about-breast-cancer\/metastases-and-staging\/\" class=\"elementor-item\">Metastases and Staging<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2519\"><a href=\"https:\/\/rftcjapan.org\/en\/about-breast-cancer\/early-stage-breast-cancers-non-invasive\/\" class=\"elementor-item\">Early-Stage Breast Cancers (Non-invasive)<\/a><\/li>\n<\/ul>\t\t\t<\/nav>\n\t\t\t\t\t\t<nav class=\"elementor-nav-menu--dropdown elementor-nav-menu__container\" aria-hidden=\"true\">\n\t\t\t\t<ul id=\"menu-2-c981917\" class=\"elementor-nav-menu sm-vertical\"><li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2521\"><a href=\"https:\/\/rftcjapan.org\/en\/about-breast-cancer\/signs-and-symptoms\/\" class=\"elementor-item\" tabindex=\"-1\">Signs and Symptoms<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2522\"><a href=\"https:\/\/rftcjapan.org\/en\/about-breast-cancer\/the-stages-of-breast-cancer\/\" class=\"elementor-item\" tabindex=\"-1\">The Stages of Breast Cancer<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2523\"><a href=\"https:\/\/rftcjapan.org\/en\/about-breast-cancer\/tumor-size-and-staging\/\" class=\"elementor-item\" tabindex=\"-1\">Tumor Size and Staging<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2520\"><a href=\"https:\/\/rftcjapan.org\/en\/about-breast-cancer\/metastases-and-staging\/\" class=\"elementor-item\" tabindex=\"-1\">Metastases and Staging<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2519\"><a href=\"https:\/\/rftcjapan.org\/en\/about-breast-cancer\/early-stage-breast-cancers-non-invasive\/\" class=\"elementor-item\" tabindex=\"-1\">Early-Stage Breast Cancers (Non-invasive)<\/a><\/li>\n<\/ul>\t\t\t<\/nav>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-2330\" class=\"elementor-element elementor-element-dd578e0 e-con-full e-flex e-con e-child\" data-id=\"dd578e0\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-6342a8d elementor-widget elementor-widget-heading\" data-id=\"6342a8d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">Risk Factors &amp; Genetics<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-857c29f elementor-nav-menu--dropdown-none elementor-widget elementor-widget-nav-menu\" data-id=\"857c29f\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;layout&quot;:&quot;vertical&quot;,&quot;submenu_icon&quot;:{&quot;value&quot;:&quot;&lt;svg aria-hidden=\\&quot;true\\&quot; class=\\&quot;e-font-icon-svg e-fas-caret-down\\&quot; viewBox=\\&quot;0 0 320 512\\&quot; xmlns=\\&quot;http:\\\/\\\/www.w3.org\\\/2000\\\/svg\\&quot;&gt;&lt;path d=\\&quot;M31.3 192h257.3c17.8 0 26.7 21.5 14.1 34.1L174.1 354.8c-7.8 7.8-20.5 7.8-28.3 0L17.2 226.1C4.6 213.5 13.5 192 31.3 192z\\&quot;&gt;&lt;\\\/path&gt;&lt;\\\/svg&gt;&quot;,&quot;library&quot;:&quot;fa-solid&quot;}}\" data-widget_type=\"nav-menu.default\">\n\t\t\t\t\t\t\t\t<nav aria-label=\"\u30e1\u30cb\u30e5\u30fc\" class=\"elementor-nav-menu--main elementor-nav-menu__container elementor-nav-menu--layout-vertical e--pointer-none\">\n\t\t\t\t<ul id=\"menu-1-857c29f\" class=\"elementor-nav-menu sm-vertical\"><li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2525\"><a href=\"https:\/\/rftcjapan.org\/en\/about-breast-cancer\/brca1-and-brca2-mutations-in-men\/\" class=\"elementor-item\">BRCA1 and BRCA2 Mutations in Men<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2526\"><a href=\"https:\/\/rftcjapan.org\/en\/about-breast-cancer\/brca1-and-brca2-mutations-in-women\/\" class=\"elementor-item\">BRCA1 and BRCA2 Mutations in Women<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2528\"><a href=\"https:\/\/rftcjapan.org\/en\/about-breast-cancer\/lobular-carcinoma-in-situ-lcis\/\" class=\"elementor-item\">Lobular Carcinoma in Situ (LCIS)<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2527\"><a href=\"https:\/\/rftcjapan.org\/en\/about-breast-cancer\/early-life-exposures\/\" class=\"elementor-item\">Early Life Exposures<\/a><\/li>\n<\/ul>\t\t\t<\/nav>\n\t\t\t\t\t\t<nav class=\"elementor-nav-menu--dropdown elementor-nav-menu__container\" aria-hidden=\"true\">\n\t\t\t\t<ul id=\"menu-2-857c29f\" class=\"elementor-nav-menu sm-vertical\"><li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2525\"><a href=\"https:\/\/rftcjapan.org\/en\/about-breast-cancer\/brca1-and-brca2-mutations-in-men\/\" class=\"elementor-item\" tabindex=\"-1\">BRCA1 and BRCA2 Mutations in Men<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2526\"><a href=\"https:\/\/rftcjapan.org\/en\/about-breast-cancer\/brca1-and-brca2-mutations-in-women\/\" class=\"elementor-item\" tabindex=\"-1\">BRCA1 and BRCA2 Mutations in Women<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2528\"><a href=\"https:\/\/rftcjapan.org\/en\/about-breast-cancer\/lobular-carcinoma-in-situ-lcis\/\" class=\"elementor-item\" tabindex=\"-1\">Lobular Carcinoma in Situ (LCIS)<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2527\"><a href=\"https:\/\/rftcjapan.org\/en\/about-breast-cancer\/early-life-exposures\/\" class=\"elementor-item\" tabindex=\"-1\">Early Life Exposures<\/a><\/li>\n<\/ul>\t\t\t<\/nav>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-2330\" class=\"elementor-element elementor-element-8382bf4 e-con-full e-flex e-con e-child\" data-id=\"8382bf4\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-f24ff62 elementor-widget elementor-widget-heading\" data-id=\"f24ff62\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">Benign Breast Conditions<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-e396cf6 elementor-nav-menu--dropdown-none elementor-widget elementor-widget-nav-menu\" data-id=\"e396cf6\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;layout&quot;:&quot;vertical&quot;,&quot;submenu_icon&quot;:{&quot;value&quot;:&quot;&lt;svg aria-hidden=\\&quot;true\\&quot; class=\\&quot;e-font-icon-svg e-fas-caret-down\\&quot; viewBox=\\&quot;0 0 320 512\\&quot; xmlns=\\&quot;http:\\\/\\\/www.w3.org\\\/2000\\\/svg\\&quot;&gt;&lt;path d=\\&quot;M31.3 192h257.3c17.8 0 26.7 21.5 14.1 34.1L174.1 354.8c-7.8 7.8-20.5 7.8-28.3 0L17.2 226.1C4.6 213.5 13.5 192 31.3 192z\\&quot;&gt;&lt;\\\/path&gt;&lt;\\\/svg&gt;&quot;,&quot;library&quot;:&quot;fa-solid&quot;}}\" data-widget_type=\"nav-menu.default\">\n\t\t\t\t\t\t\t\t<nav aria-label=\"\u30e1\u30cb\u30e5\u30fc\" class=\"elementor-nav-menu--main elementor-nav-menu__container elementor-nav-menu--layout-vertical e--pointer-none\">\n\t\t\t\t<ul id=\"menu-1-e396cf6\" class=\"elementor-nav-menu sm-vertical\"><li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-7721\"><a href=\"https:\/\/rftcjapan.org\/en\/about-breast-cancer\/chemo-side-effects\/\" class=\"elementor-item\">Chemo side effects<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2529\"><a href=\"https:\/\/rftcjapan.org\/en\/about-breast-cancer\/patient-faq\/\" class=\"elementor-item\">Patient FAQ<\/a><\/li>\n<\/ul>\t\t\t<\/nav>\n\t\t\t\t\t\t<nav class=\"elementor-nav-menu--dropdown elementor-nav-menu__container\" aria-hidden=\"true\">\n\t\t\t\t<ul id=\"menu-2-e396cf6\" class=\"elementor-nav-menu sm-vertical\"><li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-7721\"><a href=\"https:\/\/rftcjapan.org\/en\/about-breast-cancer\/chemo-side-effects\/\" class=\"elementor-item\" tabindex=\"-1\">Chemo side effects<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2529\"><a href=\"https:\/\/rftcjapan.org\/en\/about-breast-cancer\/patient-faq\/\" class=\"elementor-item\" tabindex=\"-1\">Patient FAQ<\/a><\/li>\n<\/ul>\t\t\t<\/nav>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-2ef27a8 e-flex e-con-boxed e-con e-parent\" data-id=\"2ef27a8\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-2e98e41 e-con-full elementor-hidden-mobile e-flex e-con e-child\" data-id=\"2e98e41\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-3e7dbfa e-con-full e-flex e-con e-child\" data-id=\"3e7dbfa\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;sticky&quot;:&quot;top&quot;,&quot;sticky_on&quot;:[&quot;desktop&quot;,&quot;tablet&quot;],&quot;sticky_offset&quot;:100,&quot;sticky_parent&quot;:&quot;yes&quot;,&quot;sticky_effects_offset&quot;:0,&quot;sticky_anchor_link_offset&quot;:0}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-1235e4b elementor-toc--minimized-on-tablet elementor-widget elementor-widget-table-of-contents\" data-id=\"1235e4b\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;headings_by_tags&quot;:[&quot;h2&quot;],&quot;exclude_headings_by_selector&quot;:[],&quot;marker_view&quot;:&quot;numbers&quot;,&quot;minimize_box&quot;:&quot;yes&quot;,&quot;minimized_on&quot;:&quot;tablet&quot;,&quot;hierarchical_view&quot;:&quot;yes&quot;,&quot;min_height&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;min_height_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;min_height_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"table-of-contents.default\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-toc__header\">\n\t\t\t\t\t\t<h2 class=\"elementor-toc__header-title\">\n\t\t\t\tTable of Contents\t\t\t<\/h2>\n\t\t\t\t\t\t\t\t\t\t<div class=\"elementor-toc__toggle-button elementor-toc__toggle-button--expand\" role=\"button\" tabindex=\"0\" aria-controls=\"elementor-toc__1235e4b\" aria-expanded=\"true\" aria-label=\"Open table of contents\"><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-angle-down\" viewBox=\"0 0 320 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M143 352.3L7 216.3c-9.4-9.4-9.4-24.6 0-33.9l22.6-22.6c9.4-9.4 24.6-9.4 33.9 0l96.4 96.4 96.4-96.4c9.4-9.4 24.6-9.4 33.9 0l22.6 22.6c9.4 9.4 9.4 24.6 0 33.9l-136 136c-9.2 9.4-24.4 9.4-33.8 0z\"><\/path><\/svg><\/div>\n\t\t\t\t<div class=\"elementor-toc__toggle-button elementor-toc__toggle-button--collapse\" role=\"button\" tabindex=\"0\" aria-controls=\"elementor-toc__1235e4b\" aria-expanded=\"true\" aria-label=\"Close table of contents\"><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-angle-up\" viewBox=\"0 0 320 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M177 159.7l136 136c9.4 9.4 9.4 24.6 0 33.9l-22.6 22.6c-9.4 9.4-24.6 9.4-33.9 0L160 255.9l-96.4 96.4c-9.4 9.4-24.6 9.4-33.9 0L7 329.7c-9.4-9.4-9.4-24.6 0-33.9l136-136c9.4-9.5 24.6-9.5 34-.1z\"><\/path><\/svg><\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<div id=\"elementor-toc__1235e4b\" class=\"elementor-toc__body\">\n\t\t\t<div class=\"elementor-toc__spinner-container\">\n\t\t\t\t<svg class=\"elementor-toc__spinner eicon-animation-spin e-font-icon-svg e-eicon-loading\" aria-hidden=\"true\" viewBox=\"0 0 1000 1000\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M500 975V858C696 858 858 696 858 500S696 142 500 142 142 304 142 500H25C25 237 238 25 500 25S975 237 975 500 763 975 500 975Z\"><\/path><\/svg>\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b47e52b elementor-widget elementor-widget-heading\" data-id=\"b47e52b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h6 class=\"elementor-heading-title elementor-size-default\">About Breast Cancer<\/h6>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-bae938b elementor-widget elementor-widget-template\" data-id=\"bae938b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"template.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-template\">\n\t\t\t\t\t<div data-elementor-type=\"section\" data-elementor-id=\"3044\" class=\"elementor elementor-3044\" data-elementor-post-type=\"elementor_library\">\n\t\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-2330\" class=\"elementor-element elementor-element-fd830c6 e-con-full e-grid e-con e-child\" data-id=\"fd830c6\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-2330\" class=\"elementor-element elementor-element-3717cd6 e-con-full e-flex e-con e-child\" data-id=\"3717cd6\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-e6c4d06 elementor-widget elementor-widget-heading\" data-id=\"e6c4d06\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">Breast Cancer Basics<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c84b33f elementor-nav-menu--dropdown-none elementor-widget elementor-widget-nav-menu\" data-id=\"c84b33f\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;layout&quot;:&quot;vertical&quot;,&quot;submenu_icon&quot;:{&quot;value&quot;:&quot;&lt;i aria-hidden=\\&quot;true\\&quot; class=\\&quot;\\&quot;&gt;&lt;\\\/i&gt;&quot;,&quot;library&quot;:&quot;&quot;}}\" data-widget_type=\"nav-menu.default\">\n\t\t\t\t\t\t\t\t<nav aria-label=\"\u30e1\u30cb\u30e5\u30fc\" class=\"elementor-nav-menu--main elementor-nav-menu__container elementor-nav-menu--layout-vertical e--pointer-none\">\n\t\t\t\t<ul id=\"menu-1-c84b33f\" class=\"elementor-nav-menu sm-vertical\"><li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2517\"><a href=\"https:\/\/rftcjapan.org\/en\/about-breast-cancer\/what-is-breast-cancer\/\" class=\"elementor-item\">What is Breast Cancer?<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2515\"><a href=\"https:\/\/rftcjapan.org\/en\/about-breast-cancer\/breast-cancer-statistics-global-japan\/\" class=\"elementor-item\">Breast Cancer Statistics (Global &amp; Japan)<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2516\"><a href=\"https:\/\/rftcjapan.org\/en\/about-breast-cancer\/understanding-the-risk-of-breast-cancer\/\" class=\"elementor-item\">Understanding the Risk of Breast Cancer<\/a><\/li>\n<\/ul>\t\t\t<\/nav>\n\t\t\t\t\t\t<nav class=\"elementor-nav-menu--dropdown elementor-nav-menu__container\" aria-hidden=\"true\">\n\t\t\t\t<ul id=\"menu-2-c84b33f\" class=\"elementor-nav-menu sm-vertical\"><li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2517\"><a href=\"https:\/\/rftcjapan.org\/en\/about-breast-cancer\/what-is-breast-cancer\/\" class=\"elementor-item\" tabindex=\"-1\">What is Breast Cancer?<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2515\"><a href=\"https:\/\/rftcjapan.org\/en\/about-breast-cancer\/breast-cancer-statistics-global-japan\/\" class=\"elementor-item\" tabindex=\"-1\">Breast Cancer Statistics (Global &amp; Japan)<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2516\"><a href=\"https:\/\/rftcjapan.org\/en\/about-breast-cancer\/understanding-the-risk-of-breast-cancer\/\" class=\"elementor-item\" tabindex=\"-1\">Understanding the Risk of Breast Cancer<\/a><\/li>\n<\/ul>\t\t\t<\/nav>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-2330\" class=\"elementor-element elementor-element-67a9bd1 e-con-full e-flex e-con e-child\" data-id=\"67a9bd1\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-ed0de9e elementor-widget elementor-widget-heading\" data-id=\"ed0de9e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">Diagnosis &amp; Staging<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c981917 elementor-nav-menu--dropdown-none elementor-widget elementor-widget-nav-menu\" data-id=\"c981917\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;layout&quot;:&quot;vertical&quot;,&quot;submenu_icon&quot;:{&quot;value&quot;:&quot;&lt;svg aria-hidden=\\&quot;true\\&quot; class=\\&quot;e-font-icon-svg e-fas-caret-down\\&quot; viewBox=\\&quot;0 0 320 512\\&quot; xmlns=\\&quot;http:\\\/\\\/www.w3.org\\\/2000\\\/svg\\&quot;&gt;&lt;path d=\\&quot;M31.3 192h257.3c17.8 0 26.7 21.5 14.1 34.1L174.1 354.8c-7.8 7.8-20.5 7.8-28.3 0L17.2 226.1C4.6 213.5 13.5 192 31.3 192z\\&quot;&gt;&lt;\\\/path&gt;&lt;\\\/svg&gt;&quot;,&quot;library&quot;:&quot;fa-solid&quot;}}\" data-widget_type=\"nav-menu.default\">\n\t\t\t\t\t\t\t\t<nav aria-label=\"\u30e1\u30cb\u30e5\u30fc\" class=\"elementor-nav-menu--main elementor-nav-menu__container elementor-nav-menu--layout-vertical e--pointer-none\">\n\t\t\t\t<ul id=\"menu-1-c981917\" class=\"elementor-nav-menu sm-vertical\"><li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2521\"><a href=\"https:\/\/rftcjapan.org\/en\/about-breast-cancer\/signs-and-symptoms\/\" class=\"elementor-item\">Signs and Symptoms<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2522\"><a href=\"https:\/\/rftcjapan.org\/en\/about-breast-cancer\/the-stages-of-breast-cancer\/\" class=\"elementor-item\">The Stages of Breast Cancer<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2523\"><a href=\"https:\/\/rftcjapan.org\/en\/about-breast-cancer\/tumor-size-and-staging\/\" class=\"elementor-item\">Tumor Size and Staging<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2520\"><a href=\"https:\/\/rftcjapan.org\/en\/about-breast-cancer\/metastases-and-staging\/\" class=\"elementor-item\">Metastases and Staging<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2519\"><a href=\"https:\/\/rftcjapan.org\/en\/about-breast-cancer\/early-stage-breast-cancers-non-invasive\/\" class=\"elementor-item\">Early-Stage Breast Cancers (Non-invasive)<\/a><\/li>\n<\/ul>\t\t\t<\/nav>\n\t\t\t\t\t\t<nav class=\"elementor-nav-menu--dropdown elementor-nav-menu__container\" aria-hidden=\"true\">\n\t\t\t\t<ul id=\"menu-2-c981917\" class=\"elementor-nav-menu sm-vertical\"><li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2521\"><a href=\"https:\/\/rftcjapan.org\/en\/about-breast-cancer\/signs-and-symptoms\/\" class=\"elementor-item\" tabindex=\"-1\">Signs and Symptoms<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2522\"><a href=\"https:\/\/rftcjapan.org\/en\/about-breast-cancer\/the-stages-of-breast-cancer\/\" class=\"elementor-item\" tabindex=\"-1\">The Stages of Breast Cancer<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2523\"><a href=\"https:\/\/rftcjapan.org\/en\/about-breast-cancer\/tumor-size-and-staging\/\" class=\"elementor-item\" tabindex=\"-1\">Tumor Size and Staging<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2520\"><a href=\"https:\/\/rftcjapan.org\/en\/about-breast-cancer\/metastases-and-staging\/\" class=\"elementor-item\" tabindex=\"-1\">Metastases and Staging<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2519\"><a href=\"https:\/\/rftcjapan.org\/en\/about-breast-cancer\/early-stage-breast-cancers-non-invasive\/\" class=\"elementor-item\" tabindex=\"-1\">Early-Stage Breast Cancers (Non-invasive)<\/a><\/li>\n<\/ul>\t\t\t<\/nav>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-2330\" class=\"elementor-element elementor-element-dd578e0 e-con-full e-flex e-con e-child\" data-id=\"dd578e0\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-6342a8d elementor-widget elementor-widget-heading\" data-id=\"6342a8d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">Risk Factors &amp; Genetics<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-857c29f elementor-nav-menu--dropdown-none elementor-widget elementor-widget-nav-menu\" data-id=\"857c29f\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;layout&quot;:&quot;vertical&quot;,&quot;submenu_icon&quot;:{&quot;value&quot;:&quot;&lt;svg aria-hidden=\\&quot;true\\&quot; class=\\&quot;e-font-icon-svg e-fas-caret-down\\&quot; viewBox=\\&quot;0 0 320 512\\&quot; xmlns=\\&quot;http:\\\/\\\/www.w3.org\\\/2000\\\/svg\\&quot;&gt;&lt;path d=\\&quot;M31.3 192h257.3c17.8 0 26.7 21.5 14.1 34.1L174.1 354.8c-7.8 7.8-20.5 7.8-28.3 0L17.2 226.1C4.6 213.5 13.5 192 31.3 192z\\&quot;&gt;&lt;\\\/path&gt;&lt;\\\/svg&gt;&quot;,&quot;library&quot;:&quot;fa-solid&quot;}}\" data-widget_type=\"nav-menu.default\">\n\t\t\t\t\t\t\t\t<nav aria-label=\"\u30e1\u30cb\u30e5\u30fc\" class=\"elementor-nav-menu--main elementor-nav-menu__container elementor-nav-menu--layout-vertical e--pointer-none\">\n\t\t\t\t<ul id=\"menu-1-857c29f\" class=\"elementor-nav-menu sm-vertical\"><li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2525\"><a href=\"https:\/\/rftcjapan.org\/en\/about-breast-cancer\/brca1-and-brca2-mutations-in-men\/\" class=\"elementor-item\">BRCA1 and BRCA2 Mutations in Men<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2526\"><a href=\"https:\/\/rftcjapan.org\/en\/about-breast-cancer\/brca1-and-brca2-mutations-in-women\/\" class=\"elementor-item\">BRCA1 and BRCA2 Mutations in Women<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2528\"><a href=\"https:\/\/rftcjapan.org\/en\/about-breast-cancer\/lobular-carcinoma-in-situ-lcis\/\" class=\"elementor-item\">Lobular Carcinoma in Situ (LCIS)<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2527\"><a href=\"https:\/\/rftcjapan.org\/en\/about-breast-cancer\/early-life-exposures\/\" class=\"elementor-item\">Early Life Exposures<\/a><\/li>\n<\/ul>\t\t\t<\/nav>\n\t\t\t\t\t\t<nav class=\"elementor-nav-menu--dropdown elementor-nav-menu__container\" aria-hidden=\"true\">\n\t\t\t\t<ul id=\"menu-2-857c29f\" class=\"elementor-nav-menu sm-vertical\"><li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2525\"><a href=\"https:\/\/rftcjapan.org\/en\/about-breast-cancer\/brca1-and-brca2-mutations-in-men\/\" class=\"elementor-item\" tabindex=\"-1\">BRCA1 and BRCA2 Mutations in Men<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2526\"><a href=\"https:\/\/rftcjapan.org\/en\/about-breast-cancer\/brca1-and-brca2-mutations-in-women\/\" class=\"elementor-item\" tabindex=\"-1\">BRCA1 and BRCA2 Mutations in Women<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2528\"><a href=\"https:\/\/rftcjapan.org\/en\/about-breast-cancer\/lobular-carcinoma-in-situ-lcis\/\" class=\"elementor-item\" tabindex=\"-1\">Lobular Carcinoma in Situ (LCIS)<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2527\"><a href=\"https:\/\/rftcjapan.org\/en\/about-breast-cancer\/early-life-exposures\/\" class=\"elementor-item\" tabindex=\"-1\">Early Life Exposures<\/a><\/li>\n<\/ul>\t\t\t<\/nav>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-2330\" class=\"elementor-element elementor-element-8382bf4 e-con-full e-flex e-con e-child\" data-id=\"8382bf4\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-f24ff62 elementor-widget elementor-widget-heading\" data-id=\"f24ff62\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">Benign Breast Conditions<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-e396cf6 elementor-nav-menu--dropdown-none elementor-widget elementor-widget-nav-menu\" data-id=\"e396cf6\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;layout&quot;:&quot;vertical&quot;,&quot;submenu_icon&quot;:{&quot;value&quot;:&quot;&lt;svg aria-hidden=\\&quot;true\\&quot; class=\\&quot;e-font-icon-svg e-fas-caret-down\\&quot; viewBox=\\&quot;0 0 320 512\\&quot; xmlns=\\&quot;http:\\\/\\\/www.w3.org\\\/2000\\\/svg\\&quot;&gt;&lt;path d=\\&quot;M31.3 192h257.3c17.8 0 26.7 21.5 14.1 34.1L174.1 354.8c-7.8 7.8-20.5 7.8-28.3 0L17.2 226.1C4.6 213.5 13.5 192 31.3 192z\\&quot;&gt;&lt;\\\/path&gt;&lt;\\\/svg&gt;&quot;,&quot;library&quot;:&quot;fa-solid&quot;}}\" data-widget_type=\"nav-menu.default\">\n\t\t\t\t\t\t\t\t<nav aria-label=\"\u30e1\u30cb\u30e5\u30fc\" class=\"elementor-nav-menu--main elementor-nav-menu__container elementor-nav-menu--layout-vertical e--pointer-none\">\n\t\t\t\t<ul id=\"menu-1-e396cf6\" class=\"elementor-nav-menu sm-vertical\"><li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-7721\"><a href=\"https:\/\/rftcjapan.org\/en\/about-breast-cancer\/chemo-side-effects\/\" class=\"elementor-item\">Chemo side effects<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2529\"><a href=\"https:\/\/rftcjapan.org\/en\/about-breast-cancer\/patient-faq\/\" class=\"elementor-item\">Patient FAQ<\/a><\/li>\n<\/ul>\t\t\t<\/nav>\n\t\t\t\t\t\t<nav class=\"elementor-nav-menu--dropdown elementor-nav-menu__container\" aria-hidden=\"true\">\n\t\t\t\t<ul id=\"menu-2-e396cf6\" class=\"elementor-nav-menu sm-vertical\"><li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-7721\"><a href=\"https:\/\/rftcjapan.org\/en\/about-breast-cancer\/chemo-side-effects\/\" class=\"elementor-item\" tabindex=\"-1\">Chemo side effects<\/a><\/li>\n<li class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-2529\"><a href=\"https:\/\/rftcjapan.org\/en\/about-breast-cancer\/patient-faq\/\" class=\"elementor-item\" tabindex=\"-1\">Patient FAQ<\/a><\/li>\n<\/ul>\t\t\t<\/nav>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-625a8f7 e-con-full e-flex e-con e-child\" data-id=\"625a8f7\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-a35d485 elementor-widget elementor-widget-heading\" data-id=\"a35d485\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h1 class=\"elementor-heading-title elementor-size-default\">Signs and Symptoms<\/h1>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-94f391e elementor-widget elementor-widget-text-editor\" data-id=\"94f391e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>Early detection saves lives. Knowing what to look for\u2014and acting quickly when you notice changes\u2014can make all the difference. Below are the most common signs and symptoms to watch for.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-fb3ece1 elementor-widget elementor-widget-image\" data-id=\"fb3ece1\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"800\" height=\"600\" src=\"https:\/\/rftcjapan.org\/wpdata\/wp-content\/uploads\/2026\/02\/signs-breast-cancer.svg\" class=\"attachment-large size-large wp-image-7034\" alt=\"\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-62da15f e-con-full e-flex e-con e-child\" data-id=\"62da15f\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-a366db8 elementor-widget elementor-widget-heading\" data-id=\"a366db8\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">A New Lump or Thickening<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-35fa321 elementor-widget elementor-widget-text-editor\" data-id=\"35fa321\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>A firm, irregular, or unusual lump in the breast, upper chest, or underarm area is the most common early sign. Not all lumps are cancer, but all should be checked by a doctor.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-0200875 e-con-full e-flex e-con e-child\" data-id=\"0200875\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-b60f0a3 elementor-widget elementor-widget-heading\" data-id=\"b60f0a3\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Changes in Breast Size or Shape<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-984189c elementor-widget elementor-widget-text-editor\" data-id=\"984189c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>Look for noticeable differences between breasts, swelling in one area, or a new change in contour that wasn\u2019t present before.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-7e9915a e-con-full e-flex e-con e-child\" data-id=\"7e9915a\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-d627e6f elementor-widget elementor-widget-heading\" data-id=\"d627e6f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Skin Changes<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-09e6bb6 elementor-widget elementor-widget-text-editor\" data-id=\"09e6bb6\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>Breast cancer can sometimes alter the skin\u2019s appearance. Watch for:<\/p><ul><li>Dimpling or puckering of the skin<\/li><li>Thickening of the skin<\/li><li>An orange-peel texture (known as peau d\u2019orange)<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-b953631 e-con-full e-flex e-con e-child\" data-id=\"b953631\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-adc40a0 elementor-widget elementor-widget-heading\" data-id=\"adc40a0\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Nipple Changes<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-e69335e elementor-widget elementor-widget-text-editor\" data-id=\"e69335e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>Any new change is important. You may notice:<\/p><ul><li>Nipple turning inward (inversion)<\/li><li>Persistent itching or pain<\/li><li>Scaling or crusting around the nipple<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-667fdb5 e-con-full e-flex e-con e-child\" data-id=\"667fdb5\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-0e1eab1 elementor-widget elementor-widget-heading\" data-id=\"0e1eab1\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Nipple Discharge<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-d572b9d elementor-widget elementor-widget-text-editor\" data-id=\"d572b9d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>Unexpected discharge\u2014especially if it\u2019s clear or bloody\u2014should be evaluated promptly, even if it happens only once.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-5707932 e-con-full e-flex e-con e-child\" data-id=\"5707932\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-173dd13 elementor-widget elementor-widget-heading\" data-id=\"173dd13\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Redness, Warmth, or Swelling<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3f0b0b0 elementor-widget elementor-widget-text-editor\" data-id=\"3f0b0b0\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>Red or inflamed skin that does not improve could indicate an infection or, in rare cases, inflammatory breast cancer. Seek medical guidance if symptoms persist.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-048f193 e-con-full e-flex e-con e-child\" data-id=\"048f193\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-1098059 elementor-widget elementor-widget-heading\" data-id=\"1098059\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Persistent Breast or Nipple Pain<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-9daf996 elementor-widget elementor-widget-text-editor\" data-id=\"9daf996\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>Pain that does not change with your menstrual cycle or lasts for more than two weeks should be assessed.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-1e95315 e-con-full e-flex e-con e-child\" data-id=\"1e95315\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-844719f elementor-widget elementor-widget-heading\" data-id=\"844719f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Swollen Lymph Nodes<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3f7e983 elementor-widget elementor-widget-text-editor\" data-id=\"3f7e983\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>Lumps or swelling under the arm or near the collarbone may be an early sign of breast cancer, even before a breast lump is felt.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-9511154 e-con-full e-flex e-con e-child\" data-id=\"9511154\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t<div class=\"elementor-element elementor-element-74aacb4 e-con-full section-s e-flex e-con e-child\" data-id=\"74aacb4\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t<div class=\"elementor-element elementor-element-5464e8f e-con-full e-flex e-con e-child\" data-id=\"5464e8f\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-92d29e6 elementor-widget elementor-widget-heading\" data-id=\"92d29e6\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h5 class=\"elementor-heading-title elementor-size-default\">Note<\/h5>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4834020 elementor-widget elementor-widget-heading\" data-id=\"4834020\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">When to Contact a Healthcare Provider<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3a3c3f0 elementor-widget elementor-widget-text-editor\" data-id=\"3a3c3f0\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>If you notice any new or unusual breast change, schedule a clinical breast exam. Most symptoms are not cancer, but only a medical professional can determine the cause.<\/p><p>For those at higher risk\u2014due to age, family history, or genetic factors\u2014regular screenings and self-awareness are especially important.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-a4674b8 elementor-absolute elementor-view-default elementor-widget elementor-widget-icon\" data-id=\"a4674b8\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;_position&quot;:&quot;absolute&quot;}\" data-widget_type=\"icon.default\">\n\t\t\t\t\t\t\t<div class=\"elementor-icon-wrapper\">\n\t\t\t<div class=\"elementor-icon\">\n\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-bookmark\" viewBox=\"0 0 384 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M0 512V48C0 21.49 21.49 0 48 0h288c26.51 0 48 21.49 48 48v464L192 400 0 512z\"><\/path><\/svg>\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>About Breast Cancer Breast Cancer Basics What is Breast Cancer? Breast Cancer Statistics (Global &amp; Japan) Understanding the Risk of Breast Cancer What is Breast Cancer? Breast Cancer Statistics (Global &amp; Japan) Understanding the Risk of Breast Cancer Diagnosis &amp; Staging Signs and Symptoms The Stages of Breast Cancer Tumor Size and Staging Metastases and [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":27,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-1858","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Signs and Symptoms - RFTC Japan<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/rftcjapan.org\/en\/about-breast-cancer\/signs-and-symptoms\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Signs and Symptoms - RFTC Japan\" \/>\n<meta property=\"og:description\" content=\"About Breast Cancer Breast Cancer Basics What is Breast Cancer? 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Breast Cancer Statistics (Global &amp; Japan) Understanding the Risk of Breast Cancer What is Breast Cancer? 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